Tuesday, March 20, 2007

Resistance to antibiotics

We have over-prescribed antibiotics, even those not treatable by antibiotics. Sinusitis, a common and chronic ailment is typically a viral infection and yet antibiotics has typically been prescribed between 70 - 80% to fight it, although it is applicable for bacterial infections.

For an abstract detailing the results of a four-year study, click here:
"Treatment of Acute and Chronic Rhinosinusitis in the United States, 1999-2002"

Click here for a Sinusitis Fact Sheet from the US National Institute of Health.

Click here to read the article: "Too Many Antibiotics Prescribed For Sinus Infections"

Thursday, August 04, 2005

Metabolic Equivalent Task - MET - and what is right for you

Found the article below (http://www.washingtonpost.com/wp-dyn/content/article/2005/08/03/AR2005080301635.html)
of interest.

More links to the righ where you can see charts measuring MET for all sorts of activities.

Exercise Guidelines for Women Established

By STEPHANIE NANO
The Associated Press
Wednesday, August 3, 2005; 8:23 PM

NEW YORK -- For the first time, researchers have established how much exercise women should be able to do for their age and found that their capacity is slightly lower than men's. It also declines a bit faster than men's as they grow older.

Women whose exercise capacity was less than 85 percent of what it should be were twice as likely to die within eight years, the researchers found.



Dr. Martha Gulati stands on a treadmill at the Wellness Institute at Northwestern Memorial Hospital Tuesday, Aug. 2, 2005 in Chicago. Gulati and other researchers devised a fitness chart for women that can be used to gauge your fitness by age. Until now, the only such fitness chart was based on men.  (AP Photo/M. Spencer Green)
Dr. Martha Gulati stands on a treadmill at the Wellness Institute at Northwestern Memorial Hospital Tuesday, Aug. 2, 2005 in Chicago. Gulati and other researchers devised a fitness chart for women that can be used to gauge your fitness by age. Until now, the only such fitness chart was based on men. (AP Photo/M. Spencer Green) (M. Spencer Green - AP)

Until now, the only guidelines available were based on men and it wasn't certain whether they applied to women as well. But as more women are being included in medical research, gender differences in some diseases and other health issues are emerging.

The researchers found that to be true for fitness levels. They used the results of 5,721 exercise stress tests on women over 35 to figure out what should be considered normal for them compared to the established fitness levels for men.

"In general, women's fitness levels seem to be lower regardless of her age than for men," said Dr. Martha Gulati, a Chicago cardiologist who led the study.

While fitness declines with age for everyone, the research showed the difference between men and women becomes more pronounced with age, she said. Women lose about 1 percent of their exercise capacity per year, their study found.

"Given that we live longer, it just emphasizes the importance of fitness for women," said Gulati, who along with a fellow researcher has a patent pending for the fitness guidelines.

Their findings are reported in Thursday's New England Journal of Medicine.

Treadmill stress tests are routinely used to diagnose heart disease, often after someone complains of symptoms such as chest pains or shortness of breath. The heart's activity is monitored while the person walks on the treadmill. The tests cost about $900 at Northwestern Memorial Hospital where Gulati works.

The 5,721 Chicago area women who took the treadmill test in 1992, however, didn't have any symptoms or history of heart problems. They were given a standard stress test with the speed and incline of the treadmill increased every three minutes until they became tired or had other problems.

Their exercise capacity was estimated in metabolic equivalents (METs), based on the speed and grade of the treadmill. One MET is the amount of energy or oxygen used to sit quietly for a minute. Moderate walking burns 3 to 6 METs per minute; running consumes more than 6 METs.

Using data from the volunteers, the researchers came up with a formula to determine the normal fitness level for women. A 50-year-old woman, for example, should be able to reach 8.2 METs. For a 50-year-old man, the predicted exercise capacity is 9.2 METs, based on a different equation.


Although stress tests are relatively inexpensive, Gulati said it isn't necessary to have one to find out what MET level you are achieving. Exercise machines at health clubs do the calculation automatically.

"All of them spit out how many METs you're doing depending on how hard you're working," she said. "A lot of people don't know what it means."



Dr. Gerald Fletcher, a cardiologist at the Mayo Clinic in Jacksonville, Fla., and a spokesman for the American Heart Association, said the guidelines for women will help doctors encourage patients with poor fitness levels to get more exercise to reach their expected MET level.

"Overall, I think this is a very good guideline to be done carefully in people who are not at high risk," he said.

Gulati and her colleagues also tested their fitness equation to see how well it predicted survival during the eight years the volunteers were followed and in another group of 4,471 women with heart-disease symptoms who were followed for five years.

In both groups, women who did under 85 percent of their MET level had twice the risk of death compared to those who did more than 85 percent.

In an accompanying editorial, Drs. William E. Kraus and Pamela S. Douglas suggest that doctors should ask their patients about their exercise habits during each office visit and pay more attention to the fitness levels of those who have stress tests.

"We hope that this report will provide a stimulus to reintroduce fitness assessments into the routine clinical environment for both women and men," they wrote.

Thursday, July 28, 2005

Beta-Blocking your memories?

Reading this made me think of Brave New World... Imagine a world where your bad memories are blocked. Who's to say that such neurotransmitters as described in the article will not inadvertently block out good memories? Or be used as a weapon? As with date rape drugs administered to unsuspecting women, imagine your memories being wiped out by criminals who want to ensure crimes cannot be reported by witnesses, for example.

Say your child dies of a disease - would you prefer to forget you ever had a child to forever ease the pain? Would you want a soldier with no memory and eventually, no conscience? Is that where this type of medicine is going??

The article follows (the original link on the right.)

Beta-blockers 'blot out memories'

A common blood pressure drug could help people who have witnessed traumatic events, such as the London bombings, to block out their distressing memories.

Cornell University psychiatrists are carrying out tests using beta-blockers, the journal Nature reports.

The drug has been shown to interfere with the way the brain stores memories.

Post-traumatic stress disorder affects around one in three of people caught up in such events, and memories can be triggered just by a sound or smell.

If soldiers did something that ended up with children getting killed, do you want to give them beta blockers so that they can do it again?
- Dr Paul McHugh, Johns Hopkins University

People with PTSD are given counselling, but because it is not always effective, researchers have been looking for alternative therapies.

However there are concerns that a drug which can alter memories could be misused, perhaps by the military who may want soldiers to become desensitised to violence.

Fear and memory linked

The beta-blocker propranolol has been found to block the neurotransmitters involved in laying down memories.

Studies have shown that rats who have learned to fear a tone followed by an electric shock lose that fear if propranolol is administered after the tone starts.

The Cornell University team are reported to be seeing similar results in early studies in humans, Nature reports.

Margaret Altemus, who is one of the psychiatrists working on the study, told the journal: "The memory of the event is associated with the fear, and they always occur together."

The researchers plan to recruit 60 patients for a clinical trial where participants would be asked to take a dose of propranolol whenever they experienced symptoms of PTSD, such as an increased heart rate or breathing difficulties.

But so far only one person has volunteered to take part.

Dr Altemus believes patients can be reluctant to try new therapies.

She said a drug treatment could be a useful option for those with PTSD.

"People with PTSD are disabled - their communication and relationships can be crippled.

"It's a serious illness."

But other psychiatrists have expressed concern about the use of the beta-blocker in PTSD treatment.

Berthold Gersons, based at the University of Amsterdam in the Netherlands, said: "We hope it will work, but it is a simple solution."

He cautioned it may not work in all cases of PTSD.

But other experts say PTSD is a natural response to traumatic events and should not be treated with drugs.

Dr Paul McHugh, a psychiatrist at Johns Hopkins University in Baltimore, Maryland and member of the US President's Council on Bioethics expressed concern over the possible uses of the drug.

"If soldiers did something that ended up with children getting killed, do you want to give them beta blockers so that they can do it again?"

He added: "Psychiatrists are once again marching in where angels fear to tread."




Monday, July 25, 2005

Weight Loss due to hormone injections into gut

Hormones injected into the gut, signal the brain when the stomach is full. I wonder when a "patch" might be developed that releases doses safely and painlessly. Injecting into one's gut three times a day seems not only brutal, but unmanageable, especially for those people who fear needles. See the link for more...

Monday, July 11, 2005

Spices can ward off cancer?

At the Kabuki Baths in San Francisco last year, I treated myself to an Ayurvedic massage. Warm oil slowly drizzled onto my forehead for half an hour followed by a massage and then a bath in a blazing hot cedar bath in the corner of my private room.

Ayurveda is one of, if not the oldest healing science in the world. This "Science of Life" - distilled over 5,000 years in an oral tradition from accomplished Vedic masters in India, it has often been called the "Mother of all Healing." Some of the knowledge was captured in print (Sanskrit), but much of it has been lost. Many natural healing therapies and schools of thought were rooted in Ayurvedic learnings, i.e. Homeotherapy and Polarity Therapy.

After that unusual massage, I purchased my first book on the subject. In going through it, I came upon many concepts and suggested practices that seemed entirely intrinsic. I am compelled to learn much more on preventive measures and lifestyles focusing on maintaining a healthy mind and body.

One area that I find fascinating is Ayurvedic herbology. The incorporation of specific herbs and spices corresponding to one's dosha (individual constitution) is highly beneficial. See the links to the right for more on recent medical findings on the role of (Ayurvedic) spices such as turmeric and curcumin in helping kill cancer cells...

Friday, July 08, 2005

Weight Gain/Loss impacts Wealth

Interesting how weight impacts people's status... A new study indicates that with significant weight loss comes a significant increase in wealth, and with significant weight gain, loss in wealth. The same may apply to smoking.

The perception of health therefore seems to encourage those around to give more... My question is, whether or not we can measure what it does for people's social interactions - whether it be in personal or business relationships?

Is a large part of this success (gained from weight loss) due perhaps to people's own self-perception? I firmly believe that if one feels good, one exudes confidence. Like the adage that when you're desperate, no one will date you... So if one has undergone a massive personal transformation - that could trigger a host of other social responses, wealth, etc. As people are drawn to confidence and good energy and employers could be compelled to reward those whom they consider go-getters. Losing significant weight requires a lot of work and discipline.

Saturday, June 25, 2005

Insomnia can lead to depression and more

One thing is for sure, sleep plays a huge role in our (mental) health. Recently there was a lot of noise about the links between obesity and lack of sleep. Now, depression can be triggered by a chronic bout of insomnia. Kids are very vulnerable. Typically they should be getting a minimum of 10 hours a night, especially as teenagers, believe it or not...

But with a growing number of overly permissive parents who let their kids have everything including a television and other devices in the bedroom, kids are sleeping less than ever. As a consequence, you've got exhausted kids with malfunctioning immune systems, thyroids bent out of shape, brain semi-fried from the unhealthy doses of electronica and more.

Then we wonder why we have so many more kids who are behaving like psychotic immorals. More and more kids are being put on anti-depressants, when what a lot of these kids probably need is more sleep, exercise and nutritious food. The very schools kids go to are a haven for the formation of bad habits. At this impressionable age, we condone candy and fried foods on campus. We eliminate funding for SPORTS. For the ARTS. For EXTRACURRICULAR activities.

This is what a growing body needs to discharge that energy, to maintain and develop their bodies. All the signals our society and the media / advertisers send back? Become a roboton. Behave like the hive. Take this pilllllllllll.... eat...........

We worry about a nipple popping out at the Super Bowl (like people do not know what breasts are) but condone hours of crappy advertising inspiring people to consume when they have no money. Consume, take out a loan, max out your credit, eat this junk. So who is surprised? Sleep is the next target. Especially in America where we have so little time for our SELVES. Work till you drop, in fact, to get by both parents will need to work in most cases. Sleep is likely seen as caviar for the body, and we know that we cannot be nice to ourselves, or take care of ourselves. For then we do not conform with the hive.

I say we institute siesta hours every day. The Italians have this right! Let's petition Congress! How about we form a new organization: NAP.ON

Any takers?